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Research Engineer - ML Infrastructure

Join Chai Discovery as a Research Engineer to optimize ML infrastructure for drug discovery in a fast-paced, innovative environment.

Location
San Francisco, United States
Compensation
Not disclosed
Level
mid
Type
full time · On-site

Posted by employer 2 days ago

First seen on Joblaze 16 hours ago

Last verified on the company career page 16 hours ago

Apply at Chai Discovery → Save job Scanned from chaidiscovery.com

Skills & Technologies

JAX PyTorch Python Flexible on stack

What you'll build

  • Develop core frameworks for model training and evaluation
  • Build training stack across model, layer, and kernel levels
  • Profile end-to-end training runs on large GPU clusters
  • Ensure new model architectures scale efficiently
  • Make ML training stack reliable

Must have

  • Strong software system design skills
  • Proficiency in Python
  • Fluency in Pytorch or JAX

Nice to have

  • Deep industry experience with AI/ML teams
  • Experience with model training and evaluation

AI in the day-to-day

Chai's models are moving beyond protein structure prediction into real-world therapeutic engineering.

Not disclosed in this posting: compensation, years of experience, visa sponsorship.

Joblaze summary

In this role, the Research Engineer focuses on enhancing the performance and reliability of machine learning models by developing core frameworks for training and evaluation. Key skills include expertise in Python and frameworks like PyTorch or JAX, along with a strong background in software system design and experience with large GPU clusters. This position is well-suited for professionals with significant industry experience in AI/ML, particularly those who have made impactful contributions to complex systems. Chai Discovery emphasizes a culture of high velocity and ownership, fostering collaboration among a dedicated team.

Joblaze insights

  • Listed today — first seen on Joblaze September 27, 2026. Last confirmed on Chai Discovery's careers page September 27, 2026.
  • Python appears in 47.5% of 461 comparable mid ai/ml roles in United States; JAX appears in 2.6% of 461 comparable mid ai/ml roles in United States.

Quick facts

Is the Research Engineer - ML Infrastructure role remote?
No — this is an on-site role in San Francisco, United States.
Where is the role based?
Chai Discovery is hiring for this position in San Francisco, United States.
What's the tech stack?
Joblaze extracted these technologies from the posting: JAX, PyTorch, Python.
What seniority level is this role?
Chai Discovery targets mid-level candidates for this position.
Is this full-time or contract?
Full-time for this Research Engineer - ML Infrastructure role at Chai Discovery.

From the original posting

About the role

Make our models performant, resource efficient and reliable at scale by developing the core frameworks for model training and evaluation, in close partnerships with fellow researchers and engineers.

  • Build our training stack across model, layer, and kernel levels; optimize workloads through parallelism, quantization, and custom kernels.

  • Profile end-to-end training runs on large GPU clusters; eliminate bottlenecks and failures; monitor throughput, utilization, and uptime.

  • Ensure new model architectures and training recipes scale efficiently, from early experiments to frontier-scale runs.

  • Make our ML training stack maximally reliable: fault tolerance, checkpointing, and deterministic orchestration for long-running, large-scale jobs.

Chai's models are moving beyond protein structure prediction into real-world therapeutic engineering. This is a chance to push the frontier of AI drug design, working alongside a rigorous and craft-obsessed team.

About you

Ideal backgrounds include deep industry experience working with top AI/ML teams on the kinds of problems and systems we describe above—with strong software system design skills, proficiency in Python, and Pytorch or JAX fluency. We look for technical spikes where you have gone deep and demonstrated exceptional impact on real-world problems and systems.

Standard company text repeated across Chai Discovery's postings is omitted here.

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