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Research Scientist I / II – High Throughput Chemistry

Join Iambic Therapeutics as a Research Scientist to drive high-throughput chemistry experiments in a collaborative environment.

Location
San Diego, CA, United States
Compensation
Not disclosed
Level
mid
Type
full time · On-site

Posted by employer 1 day ago

First seen on Joblaze 22 hours ago

Last verified on the company career page 22 hours ago

What you'll build

  • Design and execute parallel synthetic methods
  • Identify and optimize novel synthetic methodologies
  • Oversee operation of automated synthesis equipment
  • Analyze research outcomes and communicate findings
  • Troubleshoot automated processes

Must have

  • Ph.D. in Organic Chemistry or MS with 8 years of experience
  • Strong command of modern organic synthetic methods
  • Direct hands-on experience with High Throughput Chemistry
  • Experience with laboratory automation
  • Excellent written and verbal communication skills

Nice to have

  • Experience with Direct-to-Biology strategies
  • Familiarity with medicinal chemistry principles
  • Prior experience mentoring interns or junior colleagues

AI in the day-to-day

null

Requirements

Experience
0–8 years
Education
PhD

Not disclosed in this posting: compensation, visa sponsorship.

Benefits

401k Match Gym Membership Unlimited PTO Health Insurance

Joblaze summary

In this role, the Research Scientist will focus on designing and executing high-throughput synthetic methods to create extensive compound libraries. Key skills include expertise in organic synthesis, catalysis, and experience with laboratory automation and high-throughput chemistry techniques. This position is suitable for candidates with a Ph.D. in Organic Chemistry or an MS with significant industry experience, particularly those who thrive in collaborative, fast-paced environments. The team at Iambic Therapeutics emphasizes interdisciplinary collaboration, leveraging AI-driven platforms to enhance drug discovery.

Joblaze insights

  • Listed today — first seen on Joblaze September 25, 2026. Last confirmed on Iambic Therapeutics's careers page September 25, 2026.
  • Automation appears in 1% of 2944 comparable mid other roles in United States; Organic Chemistry appears in 0.1% of 2944 comparable mid other roles in United States.

Quick facts

Is the Research Scientist I / II – High Throughput Chemistry role remote?
No — this is an on-site role in San Diego, CA, United States.
How much experience is required?
0–8 years of relevant experience for this Research Scientist I / II – High Throughput Chemistry role.
Where is the role based?
Iambic Therapeutics is hiring for this position in San Diego, CA, United States.
What's the tech stack?
Joblaze extracted these technologies from the posting: Automation, High Throughput Chemistry, Liquid Handling Robotics, Organic Chemistry.
What seniority level is this role?
Iambic Therapeutics targets mid-level candidates for this position.
Is this full-time or contract?
Full-time for this Research Scientist I / II – High Throughput Chemistry role at Iambic Therapeutics.

From the original posting

JOB SUMMARY

We are seeking a highly skilled and motivated Research Scientist to join our Discovery Chemistry team at Iambic Therapeutics in San Diego, CA. In this role, the ideal candidate will exploit their strong background in organic synthesis, catalysis, and reaction development to design, optimize, and execute high-throughput experiments to drive compound library campaigns. The successful candidate will deliver impact cross-functionally with chemistry, biology, compound management, AI/ML, and software teams across the discovery pipeline, leveraging Iambic's HTE platform to accelerate and strengthen our programs. This position will be based in our San Diego Headquarters.

KEY RESPONSIBILITIES

  • Design and execute parallel synthetic methods to generate large, high-quality compound libraries.

  • Identify, develop, and optimize novel synthetic methodologies with a focus on automation compatibility and HTE scalability.

  • Apply newly developed synthetic routes from traditional bench-scale chemistry to robust, high-throughput, and automated processes.

  • Oversee the operation, maintenance, and continuous advancement of our chemistry toolkit and automated synthesis equipment.

  • Analyze research outcomes and library compound data and clearly communicate results and findings to cross-functional project teams.

  • Ensure all laboratory work is conducted in accordance with established safety protocols and best laboratory and ELN data recording practices.

  • Function as a core member of an interdisciplinary scientific team (chemistry, biology, software, and automation).

  • Proactively identify bottlenecks, troubleshoot automated processes, and develop solutions to ensure business continuity.

QUALIFICATIONS

Required:

  • Ph.D. in Organic Chemistry with 0-5 years of industry experience or MS in Organic Chemistry with a minimum of 8 years of industry experience.

  • Strong command of modern organic synthetic methods.

  • Direct hands-on experience with High Throughput Chemistry and/or Parallel Synthesis.

  • Experience with laboratory automation, liquid handling robotics, and automated analytical and purification systems.

  • Ability to thrive in a fast-paced, highly collaborative, and dynamic research environment.

  • Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences.

  • Proven ability to thrive in a fast-paced, high-volume environment where priorities and synthetic targets may shift rapidly based on biological data.

Strongly Preferred:

  • Experience with Direct-to-Biology (D2B) strategies for drug discovery.

  • Familiarity with the principles of medicinal chemistry.

  • Prior experience mentoring interns or junior colleagues.

ABOUT IAMBIC THERAPEUTICS

MISSION & CORE VALUES

PAY AND BENEFITS

Standard company text repeated across Iambic Therapeutics's postings is omitted here.

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