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Senior Project Manager, Biologics R&D - Early Pipeline Programs

Join Xaira Therapeutics as a Senior Project Manager to lead biologics R&D programs from discovery to IND-enabling studies.

Location
South San Francisco, California, United States
Compensation
$148k–$185k/yr
Level
senior
Type
full time · On-site

Posted by employer 1 day ago

First seen on Joblaze 7 hours ago

Last verified on the company career page 7 hours ago

What you'll build

  • Support day-to-day planning and coordination of biologics research programs
  • Build and maintain project timelines
  • Collaborate with scientific teams to define key project milestones
  • Facilitate cross-functional collaboration across research
  • Track project status, risks, and mitigation strategies

Must have

  • Minimum of 6+ years of industry experience
  • Hands-on biologics or drug discovery research
  • 3+ years of project management or cross-functional project leadership

Nice to have

  • Experience supporting biologics discovery programs
  • Familiarity with downstream nonclinical, CMC, and regulatory components
  • PMP, CAPM, or PMI-ACP certifications

Practical constraints

  • Position requires on-site work in the SSF office

AI in the day-to-day

Xaira is leveraging AI to transform drug discovery and development.

Requirements

Experience
6+ years
Education
Master's degree
Visa
No sponsorship (stated in posting)

Benefits

Equity/Stock Options Health Insurance

Joblaze summary

The Senior Project Manager for Biologics R&D at Xaira Therapeutics is responsible for overseeing the planning and coordination of biologics programs from early discovery through lead optimization and into IND-enabling studies. This role requires a strong scientific background in biologics R&D, along with project management skills to track timelines and manage deliverables across multiple projects. It is ideal for candidates with significant industry experience who have transitioned into project management roles, particularly those comfortable in a fast-paced startup environment.

Joblaze insights

  • Listed today — first seen on Joblaze October 7, 2026. Last confirmed on Xaira Therapeutics's careers page October 7, 2026.
  • Salary band is below the typical range for Management roles (median ~$170,000).
  • Starts above 27% of 135 comparable senior management roles in United States that list AI/ML we track (median $175,000 across 54 companies). See AI/ML salary trends
  • AI/ML appears in 19.6% of 915 comparable senior management roles in United States; Project Management appears in 3.1% of 915 comparable senior management roles in United States.

Quick facts

Is the Senior Project Manager, Biologics R&D - Early Pipeline Programs role remote?
No — this is an on-site role in South San Francisco, California, United States.
What's the salary range?
Xaira Therapeutics lists $148,000–$185,000 for this role.
How much experience is required?
At least 6 years of relevant experience for this Senior Project Manager, Biologics R&D - Early Pipeline Programs role.
Where is the role based?
Xaira Therapeutics is hiring for this position in South San Francisco, California, United States.
What's the tech stack?
Joblaze extracted these technologies from the posting: AI/ML, Project Management, biologics R&D, drug discovery.
What seniority level is this role?
Xaira Therapeutics targets senior candidates for this position.
Is this full-time or contract?
Full-time for this Senior Project Manager, Biologics R&D - Early Pipeline Programs role at Xaira Therapeutics.

From the original posting

About Xaira Therapeutics

About the Role

We are seeking a Project Manager, Biologics R&D to support the planning and coordination of biologics programs and projects across our early pipeline, beginning with one of our prioritized programs and spanning additional discovery-stage programs, from early-stage discovery through lead optimization and lead selection, with growing support into IND-enabling studies as programs advance. This role is well-suited for a candidate with a strong scientific background who has transitioned into a project or program management role or who has taken on cross-functional project management responsibilities within research settings. The ideal candidate will have hands-on experience in biologics R&D, with the ability to manage timelines, track deliverables, and partner closely with scientific leads to keep projects moving forward. You will partner closely with Program Team Leads, who own program strategy and scientific direction, and your counterpart on the lead program to ensure consistent program management practices across the portfolio.

This position emphasizes scientific understanding, team coordination, and milestone tracking, making it a strong fit for someone with a bench science background who has taken on increasing responsibility for project organization and cross-functional collaboration. This role is as comfortable managing single projects as they are multiple projects driving to the same program objective or milestone.

Key Responsibilities

Project Planning and Execution

  • Support day-to-day planning and coordination of biologics research programs, ensuring execution of key activities from discovery through lead selection and into IND-enabling work as programs advance.
  • Build and maintain project timelines that capture critical path, major milestones, dependencies, and deliverables across multiple concurrent programs at different stages of maturity.
  • Partner with scientific leads and functional stakeholders to align on scope, priorities, resources and progress.

Milestone Management & Decision Support

  • Collaborate with scientific teams to define key project milestones, decisional experiments and translate into actionable, resource-informed timelines, including stage-transition criteria such as hit-to-lead and lead selection.
  • Help compile project data, timelines, risks, value-realization, and trade-offs to support informed decision-making.
  • Coordinate and facilitate planning and documentation of decisive experiments, and update project plans based on results and next steps.

Cross-Functional Project Coordination

  • Facilitate cross-functional collaboration across research to ensure effective communication and documentation of decisions, alignment of priorities and timelines.
  • Schedule and run cross-functional meetings, ensuring clear agendas, effective documentation, and follow-up on action items.
  • Monitor interdependencies across functions and proactively identify, flag and resolve conflicts across workstreams.
  • Coordinate outsourced workstreams with CROs/CDMOs where applicable, including timeline integration and deliverable tracking.

Operational Support & Project Monitoring

  • Track project status, risks, and mitigation strategies; provide updates to internal stakeholders. Provide related insights and recommendations
  • Coordinate with functional leads to understand resource needs and potential impacts to timelines.
  • Contribute to scenario planning and contingency thinking for critical path activities
  • Identify operational challenges and recommend improvements to enhance efficiency and coordination.

Resource Coordination & Timeline Scenarios

  • Work closely with functional and team leads to understand resourcing needs, identify gaps and timeline impacts, including trade-offs across programs as well as within them.
  • Develop scenario plans for critical path development decisions to support contingency and investment planning to address potential delays, bottlenecks, or shifts in scope.

Qualifications

  • Advanced degree (MS, PhD, or equivalent) in life sciences or a related field strongly preferred.
  • Minimum of 6+ years of industry experience, including hands-on biologics or drug discovery research with demonstrated project or timeline management responsibilities; 3+ years of project management or cross-functional project leadership within research settings preferred.
  • Experience supporting biologics discovery programs through stages such as target validation, hit discovery, and lead optimization; exposure to lead selection governance or IND-enabling workstreams (developability, nonclinical safety, early CMC) is a strong plus.
  • Solid understanding of biologics discovery processes; familiarity with downstream nonclinical, CMC, and regulatory components is a plus.
  • Strong analytical, planning, and organizational skills; able to translate complex scientific ideas into clear plans.
  • Excellent communication, time management collaboration, and stakeholder management skills.
  • Experience with basic project tracking tools (Smartsheet, Confluence, Google Workspace, etc).
  • Working familiarity with project and program management principles as defined by the Program Management Institute (PMI) or similar bodies. PMP, CAPM, or PMI-ACP certifications are a plus, but note hands on experience matters more than the credential itself.
  • Please note that this position will be required to be on-site in the SSF office. Remote candidates will not be considered.

Preferred Attributes

  • Comfortable managing projects in a start-up environment which is fast-paced, cross-functional, and where processes are still being built.
  • Demonstrated ability to lead without authority and influence diverse teams.
  • Passion for science and dedication to improving patient outcomes through innovative biologics development.
  • Growth mindset with interest in advancing alongside programs as they mature toward IND-enabling development.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $148,000 - $185,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Standard company text repeated across Xaira Therapeutics's postings is omitted here.

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