Senior Director, HR Business Partner

POSITION SUMMARY

The Senior Director, Human Resources will report to the VP, Global Human Resources (HRBP for North America Commercial and Global Talent Development). This role will partner closely with Mirum’s Technical Operations, Quality, and G&A leaders and employees, providing strategic HR guidance and solutions that align with business objectives and are consistent with our company values. The Senior Director will advise on HR initiatives, coach leaders, foster organizational effectiveness, and ensure alignment between people strategies and business growth priorities.

JOB FUNCTIONS/RESPONSIBILITIES

• Serve as a trusted advisor to senior leaders, translating business strategy into people, organization, and talent priorities that support growth and business performance.
• Partner with leaders to assess organizational effectiveness, design scalable organizational structures, and lead change initiatives that enable business objectives.
• Coach and develop leaders to enhance leadership effectiveness, strengthen team performance, navigate complex employee and organizational issues, and build high-performing teams.
• Lead workforce planning, talent management, succession planning, and leadership development strategies to ensure the organization has the capabilities needed to achieve current and future goals.
• Partner with Talent Acquisition and business leaders to identify capability needs and develop strategies to attract, develop, engage, and retain top talent.
• Use workforce data, people analytics, and business insights to identify trends, assess risks, and influence talent and organizational decisions.
• Facilitate talent reviews, performance management, and development planning processes to drive a culture of accountability, growth, and high performance.
• Partner closely with HR Centers of Excellence and HRBPs globally to deliver integrated, consistent, and scalable people solutions across the organization.
• Lead or contribute to enterprise-wide HR initiatives and programs that enhance employee engagement, organizational effectiveness, and the overall employee experience.
• Manage complex employee relations matters, investigations, and organizational issues with sound judgment, objectivity, and compliance with company policies and employment laws.
• Ensure compliance with applicable employment laws and regulations while proactively identifying and mitigating people-related risks.
• Partner with the VP, Global Human Resources to continue to evolve and strengthen the HR Business Partner function, driving consistency, effectiveness, and strategic impact across the organization.

QUALIFICATIONS

Education /Experience:

• Bachelor’s degree in human resources or a related field required.
• 12+ years of HR experience, or an equivalent combination of education and experience.

Knowledge, Skills and Abilities:

• Proven ability to serve as a trusted advisor to senior leaders, translating business strategy into people, organization, and talent solutions within the biotechnology or pharmaceutical industry.
• Experience supporting organizations through growth and transformation.
• Strong business acumen with the ability to understand operational, financial, and organizational drivers of business performance and influence decision-making across all levels of the organization.
• Demonstrated expertise in organizational effectiveness, organizational design, workforce planning, and change management, including the ability to diagnose complex organizational challenges and implement practical, scalable solutions.
• Experience coaching and developing leaders and technical professionals to strengthen leadership effectiveness, team performance, and organizational capability.
• Proven success leading talent management processes, including talent reviews, succession planning, leadership development, and employee growth strategies.
• Ability to leverage workforce data and people analytics to identify trends, anticipate risks, and drive evidence-based talent and organizational decisions.
• Strong consulting, facilitation, and relationship-building skills, with the ability to influence and navigate complex organizational dynamics without direct authority.
• Skilled in managing complex employee relations matters, conducting objective investigations, and providing sound, actionable recommendations.
• Excellent written, verbal, and interpersonal communication skills with the ability to influence, educate, and build credibility across diverse audiences.
• Strong knowledge of employment laws, HR practices, and compliance requirements in a multi-state and global environment.
• Demonstrated ability to build, strengthen, and scale HR Business Partner capabilities and practices to deliver strategic value and organizational impact.

The salary range for this position is $270,000 to $290,000 USD. Compensation will be determined based on several factors including, but not limited to; skill set, years of experience, and the employee’s geographic location. Please note that the required compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits unless otherwise provided.

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