Sr Associate Scientist I or II, Medicinal Chemistry
Join Iambic Therapeutics as a Senior Associate Scientist to drive drug discovery in a collaborative, lab-based environment.
Posted by employer 2 days ago
First seen on Joblaze 1 day ago
Last verified on the company career page 1 day ago
Skills & Technologies
What you'll build
- Design, synthesize, purify, and characterize chemical compounds
- Identify and optimize reaction conditions
- Collaborate with high-throughput experimentation team
- Analyze biological and ADME-PK data
- Present results to project teams and senior leadership
Must have
- BS in Chemistry with 5+ years experience or MS in Chemistry with 3+ years experience
- Proven skills in multi-step organic synthesis
- Ability to thrive in a fast-paced, highly collaborative research environment
- Availability to work onsite in San Diego
Nice to have
- Prior exposure to high-throughput experimentation
- Familiarity with ADME-PK principles
- 5+ years of experience contributing to drug discovery projects
- Experience with molecular modeling and structure-based drug design
AI in the day-to-day
Iambic uses an AI-driven discovery and development platform for drug candidate delivery.
Requirements
- Experience
- 5+ years
- Education
- Bachelor's degree
Not disclosed in this posting: compensation, visa sponsorship.
Benefits
Joblaze summary
In this role, the Senior Associate Scientist will focus on designing, synthesizing, and characterizing chemical compounds while collaborating with various teams throughout the drug discovery process. Key skills include expertise in organic synthesis, catalysis, and medicinal chemistry, along with experience in high-throughput experimentation and data analysis. This position is ideal for candidates with a strong background in pharmaceutical or biotech environments, particularly those who thrive in collaborative settings. Iambic Therapeutics, a clinical-stage company, emphasizes a diverse and inclusive culture as it advances its innovative drug development initiatives.
Joblaze insights
- Listed yesterday — first seen on Joblaze October 7, 2026. Last confirmed on Iambic Therapeutics's careers page October 7, 2026.
- This exact title is also open at 1 other location at Iambic Therapeutics: San Diego HQ.
Quick facts
- Is the Sr Associate Scientist I or II, Medicinal Chemistry role remote?
- No — this is an on-site role in San Diego, United States.
- How much experience is required?
- At least 5 years of relevant experience for this Sr Associate Scientist I or II, Medicinal Chemistry role.
- Where is the role based?
- Iambic Therapeutics is hiring for this position in San Diego, United States.
- What's the tech stack?
- Joblaze extracted these technologies from the posting: ADME-PK, Medicinal Chemistry, catalysis, cheminformatics, organic synthesis.
- What seniority level is this role?
- Iambic Therapeutics targets senior candidates for this position.
- Is this full-time or contract?
- Full-time for this Sr Associate Scientist I or II, Medicinal Chemistry role at Iambic Therapeutics.
From the original posting
JOB SUMMARY
We are seeking a highly skilled and motivated Senior Associate Scientist to join the Chemistry team at Iambic Therapeutics headquarters in San Diego. This position offers the opportunity to work within a dynamic, cross-functional environment, collaborating closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning researchers, and software engineers throughout all stages of discovery, from hit identification and lead optimization through candidate selection. This is a laboratory-based Associate Scientist position that requires strong technical expertise in organic synthesis, catalysis, and medicinal chemistry, as well as hands-on experience in the drug discovery process and a demonstrated “drug hunter” mindset.
KEY RESPONSIBILITIES
Design, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) using modern analytical techniques such as LCMS, HPLC, and NMR, employing both individual and automated parallel synthesis approaches.
Identify and optimize reaction conditions using screening kits and other streamlined methodologies.
Collaborate with the high-throughput experimentation team to ensure the successful execution of parallel chemistry experiments.
Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning.
Partner with computational chemists to leverage machine learning insights for efficient execution of the design–make–test cycle and platform development.
Present results to project teams and senior leadership, clearly communicating data, implications, and recommendations.
QUALIFICATIONS
BS in Chemistry with 5+ years experience (pharma/biotech) or MS in Chemistry with 3+ years experience (pharma/biotech).
Proven skills in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation.
Ability to thrive in a fast-paced, highly collaborative research environment.
Availability to work onsite in San Diego.
PREFERRED QUALIFICATIONS
Prior exposure to high-throughput experimentation.
Familiarity with ADME-PK principles.
5+ years of experience contributing to drug discovery projects.
Experience with molecular modeling and structure-based drug design
ABOUT IAMBIC THERAPEUTICS
MISSION & CORE VALUES
PAY AND BENEFITS
Standard company text repeated across Iambic Therapeutics's postings is omitted here.